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Transderm Scop and Pregnancy

It is unknown whether it is safe to use Transderm Scop (scopolamine patch) during pregnancy. During animal studies, this pregnancy Category C medication caused a slight toxic effect in the embryos. Although it is unknown whether it may cause problems in pregnant women, it is known that this drug crosses the placenta.

Can Pregnant Women Use Transderm Scop?

Transderm Scop® (scopolamine patch) is a prescription medication used to prevent nausea and vomiting due to motion sickness, surgery, or anesthesia. It is unknown if the drug is safe for use during pregnancy.

What Is Pregnancy Category C?

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Transderm Scop is classified as a pregnancy Category C medication.
Pregnancy Category C is given to medicines that have not been studied in pregnant humans but do appear to cause fetal harm in animal studies. Also, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
Transderm Scop has not been adequately studied in pregnant humans, especially in the first two trimesters. It is probably not an appropriate choice for morning sickness, as there are other medications that have been more thoroughly studied. It is known for sure that scopolamine crosses the placenta to the baby.
Transderm Scop has been studied for use to prevent nausea and vomiting after cesarean sections. For this use, the patch is usually applied an hour before surgery. However, newer medications that have been more thoroughly studied in pregnant women are probably more appropriate and are now used more often.
When given to pregnant rats and rabbits at very high intravenous (IV) doses, scopolamine (the active ingredient in Transderm Scop) did not cause any problems, other than a slight toxic effect to rabbit embryos.
It is important to note, however, that animals do not always respond to medicines in the same way that humans do. Therefore, a pregnancy Category C medicine, including Transderm Scop, may be given to a pregnant woman if her healthcare provider believes that the benefits to the woman outweigh any possible risks to her unborn child.
Pregnancy and Pain

Transderm Scop Information

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