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Tobramycin Inhalation Solution

Tobramycin inhalation solution is prescribed for the treatment of a certain bacterial infection in people who have cystic fibrosis. This antibiotic works by interfering with the bacteria's ability to grow and multiply. It comes as a liquid that is turned into a mist using a nebulizer and an air compressor. This mist is inhaled twice daily. Side effects include voice changes, sore throat, and worsening cough.


What Is Tobramycin Inhalation Solution?

Tobramycin inhalation solution (Bethkis®, Tobi®) is a prescription antibiotic approved to treat people with cystic fibrosis who have the bacterium Pseudomonas aeruginosa in their lungs. It belongs to a class of medicines called aminoglycosides.
There are a couple of different tobramycin inhalation solution products available: Bethkis and Tobi. These products differ in how much active drug they contain per mL of solution (their concentration).
(Click What is Tobramycin Inhalation Solution Used For? for more information, including possible off-label uses.)

Are There Side Effects?

Just like any medicine, tobramycin inhalation solution can cause side effects. However, not everyone who uses the drug will experience problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are easily treated by you or your healthcare provider. Serious side effects are less common.
Commonly reported side effects include but are not limited to:
  • Increased cough
  • Worsening lung problems
  • Abnormal breathing sounds
  • Increased mucus production
  • Sore throat
  • Voice changes (hoarseness).
(Click Tobramycin Inhalation Solution Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)

Tobramycin Nebulizer Information

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