Drugs Home > Norpace CR and Breastfeeding

Research has shown that Norpace CR does pass through breast milk. Although no problems have yet been reported in any nursing infants, the manufacturer recommends that women not use the drug while breastfeeding. If you do take Norpace CR while nursing, watch for potential problems in your child, such as constipation, restlessness, and a change in the amount your child urinates.

Can Breastfeeding Women Take Norpace CR?

Norpace® CR (disopyramide) is a prescription medication used in the treatment of irregular heart rhythms when the heart rhythm problem is considered life-threatening. It belongs to a group of drugs known as antiarrhythmics. Norpace CR is known to pass through breast milk in humans.

More Information About Norpace CR and Breastfeeding

There have been several reports describing the use of Norpace CR by breastfeeding women. In these reports, the drug was shown to pass through breast milk; however, no problems were reported in the nursing infants. Investigators have estimated that a nursing infant would receive approximately 1.3 percent to 8 percent of the mother's daily Norpace CR dosage.
The manufacturer recommends that Norpace CR not be used in breastfeeding women due to the potential for serious side effects in a nursing child. However, other experts, including the American Academy of Pediatrics (AAP), consider the drug safe for use while breastfeeding, especially if safer medications are not an option.
If your healthcare provider recommends Norpace CR while you are breastfeeding, make sure to closely observe your infant for any potential side effects, such as:
  • Constipation
  • A change in the amount your child urinates
  • Dry eyes, nose, or mouth
  • Restlessness.
Let your child's healthcare provider know if you notice any of these symptoms, or anything else that seems out of the ordinary for your child.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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