Drugs Home > What Is Mycophenolate Mofetil Used For?

If you have a liver, kidney, or heart transplant, your healthcare provider may prescribe mycophenolate mofetil to prevent your body from rejecting the new organ. This medicine works by blocking the action of certain enzymes in the body, making the immune system less likely to attack the newly transplanted organ. Sometimes, mycophenolate mofetil may be used "off-label" to treat lupus nephritis, atopic dermatitis, and other conditions.

An Overview of Uses for Mycophenolate Mofetil

Mycophenolate mofetil (CellCept®) is a prescription "anti-rejection" medication used in combination with other medicines to prevent organ rejection after a heart, kidney, or liver transplant. It belongs to a group of medicines called immunosuppressants.
 
An organ transplant is the transfer of a healthy organ from one person (an organ donor) into another person who has a failing organ (the organ recipient). Not all organs can be transplanted. Commonly transplanted organs include the kidneys, lungs, liver, heart, pancreas, and small intestine.
 
The immune system is responsible for protecting the body against potentially harmful foreign invaders. After an organ transplant, the immune system can tell that the new organ is not a normal part of the body. As a result, it may attack the new organ and try to get rid of it; this is called transplant rejection. Transplant rejection can cause the transplanted organ to fail.
 
Most people who receive an organ transplant need to take anti-rejection medicines, such as mycophenolate mofetil, for the rest of their lives to prevent transplant rejection from occurring. Mycophenolate mofetil is used to prevent transplant rejection after a kidney, heart, or liver transplant. It is always used in combination with cyclosporine (Gengraf®, Neoral®, Sandimmune®) and a corticosteroid, or steroid medicine (such as prednisone).
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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