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Meperidine Abuse

Meperidine has a significant potential for both psychological and physical dependence and abuse. In fact, it is classified as a controlled substance, meaning there are special rules and regulations for prescribing and obtaining the medication.

When and How to Take the Drug

General considerations include the following:
  • This medication comes in tablet, oral solution (liquid), or injectable form. The injection form can be injected into a muscle (intramuscularly), under the skin (subcutaneously), or by IV (intravenously).
  • Try taking this medication with food if it seems to bother your stomach.
  • For the oral solution form, each dose is diluted in half a glass of water, since taking it undiluted can cause numbing of the mouth.
  • Do not drink alcohol while taking meperidine.
  • For the medication to work properly, it must be taken as prescribed. Do not increase your dose without your healthcare provider's approval. Do not suddenly stop taking meperidine, especially if you have taken it regularly for more than several weeks.

Meperidine Dosing Information

The dose of meperidine that your healthcare provider recommends will vary, depending on a number of factors, including:
  • The type and severity of your pain
  • How you respond to the medication
  • Your weight (for children)
  • Other medications you are taking
  • Other medical conditions you may have.
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
(Click Meperidine Dosage for more information.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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