Drugs Home > Granisetron Dosing

For the prevention of nausea and vomiting due to radiation, granisetron dosing typically starts at 2 mg once daily. To help prevent nausea and vomiting associated with chemotherapy, you can take 2 mg once daily or 1 mg twice daily. To help ensure the effectiveness of the medication, be sure to take your granisetron dosage within one hour before radiation or chemotherapy.

Granisetron Dosage: An Introduction

The dose of granisetron hydrochloride (Kytril®) that your healthcare provider recommends will vary depending on a number of factors, including:
  • Whether you are having radiation or chemotherapy
  • Other medications you may be taking
  • Other medical conditions you may have.
As is always the case, do not adjust your granisetron dose unless your healthcare provider specifically instructs you to do so.

Granisetron Dosing for Radiation

The recommended granisetron dose for the prevention of nausea and vomiting due to radiation is 2 mg once daily, taken within one hour before radiation.

Granisetron Dosing for Chemotherapy

The recommended granisetron dose for the prevention of nausea and vomiting due to chemotherapy is 2 mg once daily or 1 mg twice daily on the days of chemotherapy. Granisetron should be taken within one hour before chemotherapy (and 12 hours later, when taken twice a day).
There is also an injectable form of granisetron that can be given by IV within 30 minutes before chemotherapy.

General Granisetron Dosage Information

Considerations for people taking granisetron include the following:
  • Granisetron comes in tablet form. It is taken by mouth, usually one hour before chemotherapy or radiation. When used for radiation, it is taken once daily, and when used for chemotherapy, it is taken once or twice a day.
  • Granisetron can be taken with or without food. However, you may need to have an empty stomach for your chemotherapy or radiation. Be sure to ask your healthcare provider if you may take granisetron with food.
  • For the medication to work properly, it must be taken as prescribed.
  • If you are unsure about anything related to your granisetron dosage, please talk to your doctor, nurse, or pharmacist.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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