Drugs Home > Gabapentin Enacarbil

Important Information for Your Healthcare Provider

You should talk with your healthcare provider prior to taking this medication if you have:
  • Depression
  • A history of suicidal thoughts or actions
  • Kidney disease, such as kidney failure (renal failure)
  • Cancer
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Gabapentin Enacarbil to learn more, including information on who should not take the drug.)

How Does Gabapentin Enacarbil Work?

It is not known exactly how this medication works to treat restless legs syndrome or postherpetic neuralgia. Preliminary data suggests that gabapentin enacarbil binds to certain parts of calcium channels in the central nervous system, and this may be how it works for RLS and postherpetic neuralgia.

When and How to Take It

Some general considerations to keep in mind during treatment with gabapentin enacarbil include the following:
  • Gabapentin enacarbil comes in extended-release tablet form. It is usually taken by mouth once a day, with food, at approximately 5 p.m. (for RLS) or twice a day (for postherpetic neuralgia).
  • You must swallow the tablets whole; do not chew, cut, crush, or dissolve them, as this causes the medication to be released too quickly.
  • For this medication to work properly, it must be taken as prescribed.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
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