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How Does Fexofenadine Work?

When you come in contact with something you're allergic to, a chain reaction begins inside your body. During this chain reaction, specialized cells release powerful chemicals. Some of these chemicals can trigger swelling of the nasal passages leading to nasal congestion (a "stuffy nose"). Other chemicals, such as histamine, can cause sneezing, itching, and irritation.
Fexofenadine is classified as an antihistamine. As the name implies, Fexofenadine blocks the effects of histamine. This can relieve allergy symptoms. However, since histamine is not the cause of nasal congestion, taking fexofenadine will not help open nasal passages.

Is Fexofenadine Used in Children?

Nonprescription fexofenadine tablets and fexofenadine ODT (orally disintegrating tablets) are approved to treat seasonal allergy symptoms and chronic hives in children six years of age and older.
Nonprescription fexofenadine oral suspension (liquid) is approved to treat seasonal allergies in children as young as two years old and chronic hives in children as young as six years old.
Fexofenadine oral suspension is also approved as a prescription drug for treating chronic hives in children age six months through six years of age.

Off-Label Fexofenadine Uses

Your healthcare provider may recommend fexofenadine for something other than the conditions listed above. This is called an "off-label" use. Some off-label fexofenadine uses may include treatment for an unexplained long-term (chronic) cough or as part of asthma treatment.
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Last reviewed by: Kristi Monson, PharmD;
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