Drugs Home > Fentanyl Lozenge

The fentanyl lozenge is a prescription medication used for treating breakthrough cancer pain. The drug comes in the form of a lozenge on a handle (sometimes called a lollipop) and is used on an "as needed" basis. To use it, place the lozenge in your mouth (between the cheek and lower gum) and suck on it for 15 minutes. Possible side effects include nausea, drowsiness, and constipation.

What Is a Fentanyl Lozenge?

The fentanyl lozenge (Actiq®) is a prescription narcotic pain medication used to treat breakthrough pain (pain that "breaks through" the use of around-the-clock pain medication) in people with cancer who are also taking regularly scheduled narcotic medication for their underlying pain. It comes as a lozenge with a handle (it is sometimes called a lollipop), to be placed in the mouth between the cheek and gums.
The fentanyl lozenge is a Schedule II controlled substance. Schedule II medications have the highest abuse potential of all prescription medications. As a controlled substance, there are strict rules and regulations for prescribing and obtaining this medication.
(Click What Is Fentanyl Lozenge Used For? for more information, including possible off-label uses.)

Are There Side Effects?

Just like any medicine, a fentanyl lozenge can cause side effects. However, not everyone who uses the drug will experience problems. In fact, most people tolerate it quite well.
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
Common side effects of fentanyl lozenges may include but are not limited to:
(Click Side Effects of Fentanyl Lozenge to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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