Drugs Home > Desonide Side Effects

Although side effects are possible with desonide, they may vary, depending on the particular product that is being used. However, in general, adverse reactions tend to be limited to the skin and include a burning or stinging sensation, irritation, and temporary redness. Serious problems that require prompt medical care include psychotic reactions, bulging eyes, and cataracts.

An Introduction to Desonide Side Effects

As with any medicine, side effects are possible with desonide (Desonate®, DesOwen®, Verdeso®). However, not everyone who uses the medication will experience problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with desonide. Your healthcare provider can discuss a more complete list with you.)

Serious Side Effects of Desonide

Desonide is a steroid, and some side effects of steroids are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • High blood pressure (hypertension)
  • High blood sugar (hyperglycemia) or diabetes
  • Infections
  • Ruptured tendons
  • Psychotic reactions, such as hallucinations or extreme aggression
  • Glaucoma
  • Severe fluid retention
  • Weight gain
  • Bulging eyes
  • Osteoporosis
  • Loss of muscle
  • Fat deposits on the face and back, causing a round face and a fatty hump on the back of the neck
  • Cataracts
  • Stunted growth (in children).
  • Signs of an allergic reaction, such as:
    • Unexplained rash
    • Hives
    • Itching
    • Unexplained swelling.
In general, these serious reactions are extremely unlikely to occur when desonide is used as directed for a short period. Applying too much over too large an area, for too long may increase the risk of serious side effects. Keep in mind that such problems are much more common with systemic steroids, which are taken by mouth or injection, and are probably quite rare with desonide.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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