Drugs Home > Desonide Lotion Side Effects

A few of the possible side effects of desonide lotion include skin reactions, such as burning, stinging, and dryness. Although many reactions to this drug are minor, there are some side effects that are potentially serious and should be reported to a healthcare provider right away. Seek medical attention if you are using desonide lotion and experience hallucinations, ruptured tendons, or severe swelling.

An Introduction to Side Effects of Desonide Lotion

Just like any medicine, desonide lotion (DesOwen®) can cause side effects. However, not everyone who uses the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with desonide lotion. Your healthcare provider can discuss a more complete list with you.)

Desonide Lotion Side Effects to Report

Some side effects of desonide lotion are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • High blood pressure (hypertension)
  • High blood sugar (hyperglycemia) or diabetes
  • Infections
  • Ruptured tendons
  • Psychotic reactions, such as hallucinations or extreme aggression
  • Glaucoma
  • Severe fluid retention
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling
    • Difficulty breathing or swallowing.
In general, these serious reactions are unlikely to occur when desonide lotion is used as directed for a short period of time. Applying too much of the medicine over too large of an area, for an extended period of time, may increase the risk for serious steroid side effects.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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