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People who have medullary thyroid cancer may benefit from treatment with cabozantinib. This prescription drug is reserved for use when the cancer has progressed to other areas of the body. It comes as a capsule that is taken once a day. Your dosage will depend on how you tolerate the drug and other medications you are taking, among other factors.


What Is Cabozantinib?

Cabozantinib (Cometriq™) is a prescription medication approved to treat medullary thyroid cancer that has spread to other areas of the body. Medullary thyroid cancer is a rare type of cancer that begins in the thyroid, a gland in the neck that makes various hormones. 
(Click What Is Cabozantinib Used For? for more information on this topic, including possible off-label uses.)

Are There Side Effects?

Just like any medicine, cabozantinib can cause side effects. Although not everyone who uses the drug will experience problems, like many cancer treatments, most people will experience some type of adverse reaction during treatment.
In most cases, side effects can be effectively managed by you or your healthcare provider. Serious reactions are less common.
Common side effects of cabozantinib include but are not limited to:
  • Diarrhea
  • Redness, swelling, sores, or pain in the mouth
  • Redness, swelling, or pain on the palms of the hands or soles of the feet
  • Weight loss
  • Decreased appetite.
(Click Cabozantinib Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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