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Ecallantide is an injected medicine that is given to treat sudden hereditary angioedema (HAE) attacks. This prescription drug works by blocking the activity of a certain chemical that causes your veins to leak fluid and cause pain and swelling. Headaches, nausea, and reactions at the injection site are possible side effects.

What Is Ecallantide?

Ecallantide (Kalbitor®) is a prescription medication approved for the treatment of sudden hereditary angioedema (HAE) attacks. HAE is a rare, hereditary disease of the immune system that causes sudden swelling in certain parts of the body, such as the face, hands, feet, abdomen (stomach), and larynx (throat). This medication is given by injection and is administered just under the skin (subcutaneously).
(Click What Is Ecallantide Used For? for more information, including possible off-label uses.)

Are There Side Effects?

As with any medicine, ecallantide can cause side effects. However, not everyone who uses the drug will experience side effects. Most people tolerate it quite well.
If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
Some of the common side effects of this medication include:
  • Headache
  • Nausea
  • Diarrhea
  • Fever   
  • Injection site reactions, such as redness, itching, or bruising
  • Stuffy nose.
(Click Ecallantide Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)

Ecallantide Drug Information

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