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Dexamethasone Intravitreal Implant

Clinical Effects

In clinical studies, up to 30 percent of people with macular edema who were given the dexamethasone intravitreal implant had an improvement in vision of three or more lines on the eye chart two months after receiving the injection, compared with up to 12 percent of people given a placebo (injections with no active ingredient). People given the dexamethasone implant had a faster improvement in vision on average than those given the placebo injections.
In clinical studies of uveitis, 43 percent of people given the dexamethasone implant had a vision improvement of three or more lines on the eye chart eight weeks after the injection, compared with 7 percent of people given the placebo injections. In addition, 47 percent of the dexamethasone implant-treated group were considered free from inflammation after eight weeks, compared to 12 percent of those in the placebo group.

When and How to Use the Dexamethasone Intravitreal Implant

Some general considerations to keep in mind during treatment with the dexamethasone intravitreal implant include the following:
  • The dexamethasone intravitreal implant is injected into the vitreous humor inside the eye (this is called an intravitreal injection).
  • The dexamethasone intravitreal implant dissolves inside the eye and does not need to be removed.
  • A healthcare provider will administer the injection.
  • Your healthcare provider will monitor you closely in the days following your procedure. It is important to keep all your follow-up appointments.
  • For the medication to work properly, it must be used as prescribed.

Dosing Information

There is only one standard dosage of the dexamethasone intravitreal implant, regardless of your age or the condition being treated (click Dexamethasone Intravitreal Implant Dosage for more information).

Dexamethasone Intravitreal Implant Information

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