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Precautions and Warnings With Zolpidem Sublingual Tablet

In general, people who are taking zolpidem sublingual tablets should not consume alcohol. This medicine may also not be safe for use in people with sleep apnea, depression, or liver disease. Other safety precautions and warnings with zolpidem sublingual tablets apply to people who are taking certain medications and to women who are pregnant or breastfeeding.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking zolpidem sublingual tablets (Edluar®, Intermezzo®) if you have:
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
In addition, tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Zolpidem Sublingual Tablet Warnings and Precautions

Some warnings and precautions to be aware of prior to using this medicine include the following:
  • In January 2013, the U.S. Food and Drug Administration lowered the recommended dosage for Edluar for women and suggested that a lower dosage be considered for men as well. This change was made because the lower dosage is less likely to cause morning drowsiness, which can interfere with your ability to do anything that requires alertness, such as driving (see Zolpidem Sublingual Tablet Dosage for more information).
  • You should only take a middle-of-the-night zolpidem sublingual tablet (Intermezzo) if you have the chance for four more hours of additional sleep. You should only take a bedtime zolpidem sublingual tablet (Edluar) if you have the chance for a full night of rest (seven or eight hours). Never drive or operate heavy machinery shortly after you have taken a dose of zolpidem sublingual tablets, even if you do not feel drowsy. If for some reason you take this medicine and must wake up sooner than recommended, be aware that you may be quite drowsy and unable to drive safely.
  • If you drink alcohol, let your healthcare provider know prior to starting zolpidem sublingual tablets. In general, people should not use alcohol when taking this medication, as it can increase the risks for developing zolpidem sublingual tablet side effects.
  • If you notice any changes in your behavior, such as anything unusual or disturbing, while taking zolpidem sublingual tablets or other sleep medicines, notify your healthcare provider immediately. Bizarre thoughts or behavior have been reported with zolpidem sublingual tablets.
  • Be aware that you may get out of bed while not fully awake and do things that you may not remember, such as sleep-walking or sleep-eating. If this happens, your healthcare provider will probably recommend that you stop taking zolpidem sublingual tablets.
  • Zolpidem sublingual tablets can cause severe allergic reactions. If you have an allergic reaction to this medication, you should never take it again.
  • This sleep medicine should be used with caution in people with sleep apnea or other breathing problems, as it could make these problems worse.
  • This drug has been reported to cause or worsen depression. Let your healthcare provider know if you think you may be depressed or if your depression is becoming worse.
  • Liver disease may affect the way your body handles this product. You may need a lower zolpidem sublingual tablet dosage.
  • Zolpidem sublingual tablets are a pregnancy Category C medication. This means that the medicine may not be safe for use during pregnancy, although the full risks are currently unknown (see Intermezzo and Pregnancy or Edluar and Pregnancy).

Zolpidem Sublingual Tablet Information

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