Tripedia Drug Interactions

A number of medications may interact with Tripedia. Drug interactions can occur if the vaccine is combined with anticoagulant medicines or immunosuppressants. Children taking these medications may not receive the full benefit of the vaccine. In order to help prevent such problems, tell your child's healthcare provider about all the medicines and supplements your child is taking.

An Overview of Tripedia Interactions

Tripedia® (DTaP) is unlikely to interact with other vaccines and can be given at the same time as other childhood vaccines, with different syringes and different injection sites (except for ActHIB®, which can mixed together with Tripedia). However, Tripedia can react negatively with a few medications. Some of the medicines that may lead to drug interactions with this vaccine include:
 
  • Anticoagulants (commonly known as "blood thinners"), such as warfarin (Coumadin®, Jantoven®) or heparin
  • Immunosuppressants, such as:
 
    • Chemotherapy (as well as radiation treatment)
    • Corticosteroids, such as:
  • Betamethasone (Celestone®)
  • Cortisone
  • Dexamethasone (Decadron®)
  • Fludrocortisone (Florinef®)
  • Hydrocortisone (Cortef®)
  • Methylprednisolone (Depo-Medrol®, Medrol®)
  • Prednisolone (Pediapred®)
  • Prednisone
  • Triamcinolone (Kenalog®)
    • Cyclophosphamide (Cytoxan®)
    • Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
    • Etanercept (Enbrel®)
    • Methotrexate (Rheumatrex®)
    • Mycophenolate (CellCept®)
    • Sirolimus (Rapamune®)
    • Tacrolimus (Prograf®).
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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