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How Does It Work?

Triglide is part of a class of drugs known as fibric acid derivatives (also known as fibrates). It works by increasing the production of an enzyme (lipoprotein lipase) that breaks down triglyceride-rich particles (VLDL) and increases their removal from the body. It can also decrease the number of these particles made and released from the liver. Depending on the type of cholesterol problem you have, Triglide may also:


Since Triglide can lower both LDL cholesterol and triglyceride levels (along with lowering total cholesterol and increasing HDL), a person can decrease his or her risk of developing certain health problems in the future.
In previous clinical research studies, people taking Triglide daily were able to:
  • Reduce triglyceride levels by 20 percent to 55 percent
  • Reduce LDL cholesterol by 20 percent to 30 percent*
  • Reduce total cholesterol by 10 percent to 20 percent
  • Raise HDL cholesterol by 10 percent to 20 percent.
*In studies in which people had triglyceride levels greater than 350mg/dL, Triglide actually raised LDL levels.

When and How Do I Take It?

Some general considerations for when and how to take Triglide include:
  • The medication comes in a tablet form that is taken by mouth once a day. It should be taken with a glass of water, but may be taken with or without food.
  • Do not break, chew, or crush the tablets.
  • Triglide should be taken at the same time every day to help maintain an even level of medicine in the blood. Do not take it more often than directed.
  • For the medication to work properly, it must be taken as prescribed. It will not work if you stop taking it.
  • If you are taking a bile acid sequestrant, make sure to take your Triglide more than one hour before, or more than four hours after, the bile acid sequestrant. Bile acid sequestrants include:



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Triglide (Fenofibrate)

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