Triglide and Liver Problems

Problems with the liver are among the possible side effects of Triglide. An increase in liver enzymes and fatty change in the liver are two liver problems that can occur in some people who take this medicine. Symptoms of liver problems in people taking Triglide can include abdominal pain (or stomach pain), feeling more tired than usual, yellowing of the skin or the whites of the eyes, and nausea and vomiting, among other things. Be sure to talk with your healthcare provider if you have any questions or concerns about Triglide and liver problems.

Triglide (Fenofibrate)

Triglide and Liver Problems: An Overview

As with any medication, there are a number of possible side effects that can occur during treatment with Triglide™ (fenofibrate), including possible problems with the liver. For people taking Triglide, liver problems can include an increase in liver enzymes and fatty change in the liver.

Increases in liver enzymes occur in up to 13 percent of people taking Triglide, while fatty deposits in the liver occur in less than 1 percent of people. It is difficult to tell whether these liver problems are actually caused by the medication or something else.

Triglide and Liver Problems: High Liver Enzymes

Liver enzymes are usually measured to see if a person has liver damage. They do not measure how well the liver is working. A number of things can increase liver enzymes, including certain medicines (such as antibiotics or certain anti-inflammatory medicines), alcohol, infections (such as mononucleosis or viral hepatitis), obesity, and diabetes.

Triglide is also known to increase liver enzyme levels. Except in very rare cases, this increase in liver enzymes does not cause any symptoms. However, your doctor will measure your liver enzyme levels before you begin treatment with Triglide and several months after you start. He or she will also measure your liver enzyme levels if your Triglide dosage is increased.

If your liver enzymes are high, your doctor may continue to test them on a more frequent basis. If they remain high, your doctor may recommend lowering your Triglide dosage or switching to another cholesterol medication. In most cases, when Triglide is stopped, the liver enzymes return to their pre-Triglide levels.

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