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Drug Interactions With Tri-Legest Fe

Many Seizure Medications
Some seizure medications may cause your body to metabolize the hormones in Tri-Legest Fe too quickly, perhaps increasing your risk of pregnancy. Ask your healthcare provider if you should use a different method of contraception while taking a seizure medication.
Modafinil (Provigil)
Modafinil can make Tri-Legest Fe less effective, possibly increasing your risk of pregnancy. Talk with your healthcare provider, as you may need to use a backup method of contraception.
Protease Inhibitors
Using Tri-Legest Fe with a protease inhibitor may increase your risk of pregnancy and can make the protease inhibitor less effective. Talk with your healthcare provider before combining these two medications.
Selegiline (Eldepryl, Emsam, Zelapar)
The hormones in Tri-Legest Fe may increase the level of selegiline in your blood, perhaps increasing your risk of side effects. Your healthcare provider may need to lower your selegiline dosage or may recommend an alternate form of contraception.
St. John's Wort
St. John's wort (a commonly used herbal supplement) may decrease the effectiveness of Tri-Legest Fe, perhaps increasing the chance of pregnancy. In general, you should not take St. John's wort while using Tri-Legest Fe.

Final Thoughts on Drug Interactions With Tri-Legest Fe

It is possible that not all drug interactions with Tri-Legest Fe were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific drug interactions that may apply to you.
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