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Drug Interactions

Tocilizumab can potentially interact with a few other medications (see Drug Interactions With Tocilizumab).

Overdose Information

It is unclear what exactly to expect from an overdose with this medication. The few cases of overdoses reported did not cause any serious problems.
(Click Actemra Overdose for more information.)

What Should I Do If I Miss a Dose of Tocilizumab?

If you miss a dose of tocilizumab, contact your healthcare provider to set up an appointment for your dose as soon as possible.

How Does It Work?

Tocilizumab is an antibody that binds to a specific set of receptors known as interleukin-6 (IL-6) receptors in the body. This action prevents the interleukin-6 (which is a natural inflammatory protein) from binding to the receptor, thereby reducing the symptoms of rheumatoid arthritis and idiopathic juvenile arthritis.
Because tocilizumab targets a specific part of the immune system (IL-6), it is called a "biological response modifier," as it changes (modifies) the body's immune response. It is also known as a "biologic" medication, because it is a protein. Lastly, tocilizumab is also classified as a monoclonal antibody. Monoclonal antibodies (synthetic antibodies made in a laboratory) are a diverse group of medications used to treat a wide variety of conditions.
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Tocilizumab Drug Information

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