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Tobramycin Inhalation Solution Side Effects

Possible Side Effects

Tobramycin inhalation solution has been studied extensively in clinical trials. In these studies, the side effects that occurred in people using the medication were carefully documented and compared with the side effects that occurred in a similar group of people using a placebo (an inhalation with no active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the placebo.
 
The reported side effects differed slightly among the available tobramycin inhalation solution products. However, in clinical studies, the most commonly reported side effects of any tobramycin inhalation solution medication included:
 
  • Increased cough -- in up to 46.1 percent of people
  • Sore throat -- up to 38 percent
  • Increased mucus production -- up to 37.6 percent
  • Loss of strength -- up to 35.7 percent
  • Stuffy or runny nose -- up to 34.5 percent
  • Shortness of breath -- up to 33.7 percent
  • Fever -- up to 32.9 percent
  • Lung disorder -- up to 31.4 percent
  • Decreased forced expiratory volume (a lung test that indicates worsening lung function) -- up to 31 percent
  • Headache -- up to 26.7 percent
  • Chest pain -- up to 26 percent.
 
Other common side effects, occurring in 2 percent to 21.3 percent of people, included:
 
  • Abnormal breathing sounds
  • Change in voice (hoarseness)
  • Discolored mucus
  • Coughing up blood
  • Loss of appetite
  • Asthma
  • Nausea and vomiting
  • Abdominal (stomach) pain
  • Weight loss
  • General pain
  • Inflammation of the nasal sinuses
  • Ear pain
  • Back pain
  • Nosebleed
  • Change in taste
  • Diarrhea
  • General feelings of discomfort or ill-being
  • Lower respiratory tract infection, such as pneumonia
  • Dizziness
  • Over-breathing (unusually rapid or deep breathing)
  • Rash
  • An increase in red blood cell sedimentation rate (a blood test that can indicate inflammation in the body)
  • Wheezing
  • Inflammation of the lining of the bronchial tubes (bronchitis)
  • Inflammation of the tonsils
  • An increase in the level of a certain type of white blood cell
  • An increase in the level of antibodies in the blood.
 

Tobramycin Nebulizer Information

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