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Tobramycin Inhalation Solution and Breastfeeding

It is unknown if tobramycin inhalation solution passes through human breast milk. However, the active ingredient in the drug is known to pass through breast milk in small amounts when given as an injection. Due to the potentially serious risks associated with this drug, the manufacturer recommends that nursing women either not breastfeed or not use tobramycin inhalation solution.


Can Breastfeeding Women Use Tobramycin Inhalation Solution?

Tobramycin inhalation solution (Bethkis®, Tobi®) is a prescription antibiotic used to treat people with cystic fibrosis who have a certain lung infection. At this time, it is not entirely known whether the medication passes through breast milk. Therefore, if you are breastfeeding or plan to start, talk with your healthcare provider before using this medication.

More Research on Tobramycin Inhalation Solution and Breastfeeding

There are no studies looking at tobramycin inhalation solution in breastfeeding women. Therefore, it is not entirely known whether the drug passes through breast milk, or if it would harm a nursing child. The active ingredient in the medication (tobramycin) has been shown to pass through breast milk in small amounts when given as an injection.
However, tobramycin inhalation solution is inhaled into the lungs, not given as an injection. When used as directed, very little of the medicine actually reaches the bloodstream, where it could pass to breast milk.
Nonetheless, because tobramycin inhalation solution is associated with potentially serious side effects, the manufacturer of the medication recommends that women either breastfeed or be treated with tobramycin inhalation solution, but not do both. However, other resources state the medication is compatible with breastfeeding.
If your healthcare provider recommends tobramycin inhalation solution while breastfeeding, make sure to watch for any possible side effects in your infant. Report any possible problems to your child's healthcare provider, such as:
  • Difficulty feeding
  • Unexplained or excessive crying
  • Problems with hearing
  • Breathing problems, such as coughing or wheezing
  • Oral thrush (a yeast infection in the mouth)
  • Diarrhea
  • Diaper rash
  • Bloody stool
  • Anything else that just doesn't seem right.
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Tobramycin Nebulizer Information

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