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Precautions and Warnings With Tobramycin Inhalation Solution

Allergic reactions, drug interactions, and other problems can occur in some people using tobramycin inhalation solution. For this reason, it's a good idea to talk to your healthcare provider about the warnings and precautions before starting treatment. Tobramycin inhalation solution is not suitable for everyone, so make sure your healthcare provider is aware of any medications you are taking and any other medical conditions you have.

 

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using tobramycin inhalation solution (Bethkis®, Tobi®) if you have:
 
  • Kidney disease, such as kidney failure (renal failure)
  • Hearing problems
  • A balance disorder or dizziness
  • A disorder that affects your muscles, such as myasthenia gravis or Parkinson's disease
  • Had an organ transplant
  • Breathing problems, such as wheezing, coughing, or chest tightness
  • Any allergies, including to foods, dyes, or preservatives.
 
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
 
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 

Specific Tobramycin Inhalation Solution Precautions and Warnings

Some warnings and precautions to be aware of prior to using this drug include the following:
 
  • Aminoglycoside antibiotics, including tobramycin inhalation solution, can cause inner ear damage, which could lead to hearing loss or balance problems. Your healthcare provider may recommend hearing tests during treatment to monitor for this potential side effect. Let him or her know if you develop signs of damage to your inner ear, such as:
    • Ringing in the ears
    • Hearing loss
    • Dizziness
    • Problems with balance.
 
  • Aminoglycoside antibiotics, such as tobramycin inhalation solution, have the potential to cause kidney damage. Although kidney problems did not occur in tobramycin inhalation solution clinical trials, your healthcare provider may choose to monitor your kidney function using blood and urine tests during treatment to make sure your kidneys are working properly. If you show signs of kidney damage, you may need to stop using the medication, at least temporarily.
 
  • Tobramycin inhalation solution could worsen muscle weakness and should be used with caution in people who have conditions that affect the muscles, such as myasthenia gravis or Parkinson's disease.
 
  • This medication can cause the airways to constrict (tighten), which could lead to severe breathing problems. Let your healthcare provider know if you experience wheezing, chest tightness, coughing, or shortness of breath during treatment.
     
  • It is not known whether tobramycin inhalation solution passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to beginning treatment (see Tobramycin Inhalation Solution and Breastfeeding).
 

Tobramycin Nebulizer Information

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