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What Is Tiludronate Used For?

Tiludronate is used for the treatment of Paget's disease in adults. It is recommended for people with very high alkaline phosphate levels, who have Paget's symptoms, or who are at risk for future complications of Paget's disease. At this time, there are no universally accepted off-label tiludronate uses.

Tiludronate Uses: An Overview

Tiludronate disodium (Skelid®) is a prescription medication that is part of a group of medications known as bisphosphonates. It is approved for the treatment of Paget's disease of bone.
 
Normally, bone is continuously being broken down and rebuilt. Paget's disease of the bone is a condition involving rapid breakdown of bone combined with abnormal reformation of bone. The abnormally reformed bone is weaker than normal. Symptoms of Paget's disease can include pain and bent or broken bones. Bisphosphonates, such as tiludronate, can help slow the breakdown of bone and can help the body build bone more normally.
 
Not all people with Paget's need to be treated with a bisphosphonate. Tiludronate is recommended for people with very high alkaline phosphate levels (a measure of Paget's severity), who have Paget's symptoms, or who are at risk for future complications of Paget's disease.
 

How Does Tiludronate Work?

Tiludronate belongs to a group of medications known as bisphosphonates. The drug binds to certain cells in bones and slows the breakdown of bone. Normally, bone is continuously being broken down and rebuilt. Paget's disease of the bone is a condition involving rapid breakdown of bone combined with abnormal reformation of bone. The abnormally reformed bone is weaker than normal. Bisphosphonates, such as tiludronate, can help slow the breakdown of bone and can help the body build bone more normally.
 
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Tiludronate for Paget's Disease

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