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Side Effects of Tiludronate

Vomiting, diarrhea, and nausea are some of the most commonly reported side effects of tiludronate. There are also some less common but potentially serious tiludronate side effects that should be reported to a healthcare provider immediately, including severe heartburn, jaw or tooth problems, and difficulty swallowing. To reduce the chance of developing serious esophageal side effects, avoid eating or drinking two hours before or after taking tiludronate.

Tiludronate Side Effects: An Introduction

As with any medicine, side effects are possible with tiludronate disodium (Skelid®); however, not everyone who takes the medication will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with tiludronate. Your healthcare provider can discuss a more complete list of tiludronate side effects with you.)

Serious Side Effects Seen With Tiludronate

Some side effects with tiludronate, while occurring infrequently, are potentially serious and should be reported immediately to your healthcare provider. These include, but are not limited to:
  • Throat pain, chest pain, or difficulty swallowing (which may be signs of ulcers of the esophagus)
  • Severe heartburn or heartburn that does not go away (which may be signs of a stomach ulcer)
  • Severe bone, muscle, or joint pain
  • Jaw or tooth problems
  • Signs of an allergic reaction, including unexplained rash, hives, itching, wheezing, difficulty breathing, and unexplained swelling.
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