Drug Interactions With Tiludronate

There are many medicines that may cause drug interactions with tiludronate, including aspirin, magnesium products, iron supplements, and indomethacin. Foods and beverages may also interact with tiludronate, so it is important to avoid eating or drinking at least two hours before or after taking your dosage. Tiludronate interactions can decrease the absorption of tiludronate into the body, making the medication less effective.

Tiludronate Drug Interactions: An Overview

Tiludronate disodium (Skelid®) can potentially interact with a number of other medications. Some of the medicines that may lead to tiludronate interactions include:
 
Food and beverages (other than water) can also interact with tiludronate, preventing it from being absorbed into the body and making it less effective. Tiludronate should be taken with water in the morning on an empty stomach. Do not eat or drink anything (besides water) for two hours before or after taking your tiludronate dosage.
 

Tiludronate Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when tiludronate is combined with any of the drugs listed above.
 
Aspirin
Aspirin can decrease the absorption of tiludronate into your body, making it less effective. Do not take aspirin within two hours of taking tiludronate.
 
Calcium Products
Calcium binds to tiludronate in the stomach, preventing it from being absorbed in the body and making it less effective. While it is usually important for people with osteoporosis to take calcium, it should not be taken within two hours of taking tiludronate.

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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