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Thalomid Side Effects

In a majority of cases, people taking Thalomid will develop some type of side effect. Clinical trials have shown that some of the most commonly reported reactions to this drug include fatigue, swelling, and constipation. Although most reactions tend to be mild and easy to treat, seek medical treatment if you develop side effects like fainting, a rash, or other potentially serious problems.

An Introduction to Thalomid Side Effects

Just like any medicine, Thalomid® (thalidomide) can cause side effects. Although not everyone who uses the drug will have problems, the majority of people will experience some type of side effect during treatment.
If reactions do occur, in most cases, they are mild and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
(This article covers many, but not all, of the possible side effects with Thalomid. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects With Thalomid

Thalomid has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking Thalomid were carefully documented and compared to the side effects that occurred in a similar group of people not taking Thalomid. As a result, it was possible to see what side effects occurred and how often they appeared.
In these studies, the most common Thalomid side effects included:
  • Fatigue -- in up to 79 percent of people
  • Low blood calcium levels -- up to 72 percent
  • Swelling of the arms, hands, legs, ankles, feet, or other body areas -- up to 56 percent
  • Constipation -- up to 55 percent
  • Numbness, coldness, tingling, or burning sensations, especially of the hands and feet -- up to 54 percent
  • Shortness of breath -- up to 42 percent
  • Muscle weakness -- up to 40 percent
  • Drowsiness -- up to 37.5 percent
  • Low white blood cell counts -- up to 35 percent
  • Skin rash -- up to 30 percent.
Other common side effects, occurring in 10 percent to 28 percent of people, included but were not limited to:
  • Confusion
  • Nausea
  • Decreased appetite
  • Anxiety
  • Agitation
  • Weakness or lack of energy
  • Headache
  • Tremor
  • Dizziness or lightheadedness
  • Fever
  • Changes in weight (weight loss or gain)
  • Muscle twitching and cramping
  • Dry skin
  • Dry mouth
  • Diarrhea
  • Muscle and joint pain
  • Heartburn or indigestion
  • Acne
  • Stuffy or runny nose
  • Sweating
  • Increased blood sugar levels
  • Yeast infection of the mouth (thrush)
  • Depression.
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Thalomid Medication Information

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