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Precautions and Warnings With Testosterone Buccal Tablet

Testosterone buccal tablets may not be the best choice to treat low testosterone levels if you have kidney, liver, or heart disease. In addition, if you have breast or prostate cancer, or certain other medical conditions, do not use the testosterone buccal tablet. Reviewing these and other warnings and precautions with your healthcare provider can help ensure a safe treatment process.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using the testosterone buccal tablet (Striant™) if you have:
 
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
     
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 

Specific Warnings and Precautions With the Testosterone Buccal Tablet

Warnings and precautions to be aware of prior to using this drug include the following:
 
  • Testosterone replacement therapy (such as the testosterone buccal tablet) can worsen, or even cause, an enlarged prostate. It also appears to increase the risk of prostate cancer. Your healthcare provider should evaluate you for prostate cancer before you start the testosterone buccal tablet and periodically thereafter.
     
  • Make sure to check your gums and cheeks regularly. If anything seems abnormal, be sure to let your healthcare provider know.
     
  • The testosterone buccal tablet is not approved for use in women. It has not been adequately studied in women and can cause virilization (the development of male characteristics, such as a deep voice or body hair) in women.
     
  • The testosterone buccal tablet can potentially decrease sperm count, thereby decreasing fertility, although it can also help with certain causes of infertility related to low testosterone. Consult your healthcare provider if you experience difficulty conceiving a child while using testosterone buccal tablets.
     
  • Androgens can increase the risk of liver problems, including liver cancer. Although these problems have not been reported with the testosterone buccal tablet, they cannot be completely ruled out.
     
  • Androgens can cause fluid retention, which can be dangerous for people with liver, heart, or kidney disease.
     
  • Androgens can sometimes cause high red blood cells. This can increase the risk of blood clots. If the testosterone buccal tablet causes your red blood cells to increase too much, you will need to stop using it.
     
  • Breast enlargement can occur in men using the testosterone buccal tablet.
     
  • The testosterone buccal tablet can worsen (or possibly even cause) sleep apnea.
     
  • This product can potentially interact with a few other medications (see Drug Interactions With Testosterone Buccal Tablet).
     
  • The testosterone buccal tablet is considered a pregnancy Category X medication. This means that it is definitely not safe for use during pregnancy (see Striant and Pregnancy).
     
  • This medicine is not safe for use during breastfeeding (see Striant and Breastfeeding).
     
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Testosterone Buccal Tablet Information

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