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Precautions and Warnings With Tacrolimus

Having a history of anemia, any type of cancer, or diabetes may prevent you from taking tacrolimus safely. Precautions and warnings with this medicine include possible drug interactions and potentially serious complications, such as skin cancer, life-threatening infections, and problems with your nervous system. Other safety concerns apply to women who are pregnant or breastfeeding, as well as people with certain allergies.

What Should I Tell My Healthcare Provider?

Talk with your healthcare provider prior to taking tacrolimus (Prograf®, Protopic®) if you have:
 
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • Kidney disease, such as kidney failure (renal failure)
  • Heart problems
  • High blood pressure (hypertension)
  • Diabetes
  • Lymphoma, skin cancer, or any other type of cancer
  • A rare genetic skin condition called Netherton's syndrome
  • An infection of any kind, including chickenpox or herpes
  • Plans to receive a vaccine
  • A history of anemia
  • Been told you have electrolyte problems, such as low blood phosphate or magnesium
  • A weakened immune system due to human immunodeficiency virus (HIV), acquired immune deficiency syndrome (AIDS), or any other cause
  • Any allergies, including to foods, dyes, or preservatives.
 
Also, let your healthcare provider know if you are:
 
 
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 

Tacrolimus Drug Information

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