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Drug Interactions With Tacrolimus Ointment

Alcohol, calcium channel blockers, corticosteroids, and other drugs can interact with tacrolimus ointment. As a result, the levels of the medications in your blood may increase, which could put you at risk for potentially serious problems. To avoid complications, your healthcare provider may monitor you more closely or recommend a different medication altogether.

An Overview of Tacrolimus Ointment Interactions

Tacrolimus ointment (Protopic®) can potentially interact with several other medications. Some of the drugs that may react with tacrolimus ointment include but are not limited to:
  • Other immunosuppressants, such as:
    • Corticosteroids, such as:
      • Betamethasone (Celestone®)
      • Cortisone
      • Dexamethasone (Decadron®)
      • Fludrocortisone (Florinef®)
      • Hydrocortisone (Cortef®)
      • Methylprednisolone (Depo-Medrol®, Medrol®)
      • Prednisolone (Pediapred®)
      • Prednisone
      • Triamcinolone (Kenalog®)

Tacrolimus Ointment Information

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