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Precautions and Warnings With Sodium Picosulfate/Magnesium Oxide/Anhydrous Citric Acid

Although sodium picosulfate/magnesium oxide/anhydrous citric acid can be an effective bowel-prep product for many people, it may not be appropriate for those with an intestinal blockage, kidney disease, or a bowel perforation. Other important precautions for using sodium picosulfate/magnesium oxide/anhydrous citric acid safely include warnings of potentially serious electrolyte imbalances, colon ulcerations, and other complications.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking sodium picosulfate/magnesium oxide/anhydrous citric acid (Prepopik®) if you have:
  • Kidney disease, such as kidney failure (renal failure)
  • A history of seizures
  • Difficulty swallowing
  • Frequent vomiting
  • A hole in the bowel (bowel perforation)
  • Intestinal blockage (obstruction)
  • Signs of a bowel obstruction, such as:
    • Nausea
    • Vomiting
    • Abdominal (stomach) pain
    • Abdominal swelling (distention)
  • An electrolyte imbalance, such as low blood sodium (hyponatremia) or potassium (hypokalemia)
  • Been on a low-salt diet
  • Gastric retention (a condition in which there is a delayed emptying of stomach contents into the intestines)
  • Inflammatory bowel disease or other bowel problems, such as:
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Sodium Picosulfate/Magnesium Oxide/Anhydrous Citric Acid Information

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