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Dosing Information

The dose of sirolimus your healthcare provider recommends will vary, depending on a number of factors, including:
  • Your weight
  • Your sirolimus blood levels
  • Your risk for transplant rejection
  • Other medical conditions you may have
  • Other medications you are taking.
As is always the case, do not adjust your dose unless your healthcare provider specifically tells you to do so.
(Click Sirolimus Dosage for more information.)

Drug Interactions

Sirolimus can potentially react with a number of other medicines (see Drug Interactions With Sirolimus).

What If I Take an Overdose?

An overdose with sirolimus could be dangerous. Seek immediate medical attention if you or someone else may have taken too much of this medication.
(Click Rapamune Overdose for more information.)

How Should Sirolimus Be Stored?

Sirolimus tablets should be stored at room temperature, away from light. The oral solution should be stored in the refrigerator, protected from light. If needed, the oral solution can be stored at room temperature for up to 15 days. Once opened, the oral solution must be used within one month. Keep this and all other medications out of the reach of children and pets.
Sirolimus oral solution may develop a slight haze when refrigerated. This is normal and not a cause for concern. If a haze develops, allow the liquid to come to room temperature and gently shake it until the haze disappears.

Sirolimus Drug Information

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