Simvastatin

The prescription drug Simvastatin is licensed to treat a number of conditions related to heart disease, such as high cholesterol and high triglycerides. Simvastatin is also used to prevent cardiovascular disease. By blocking an enzyme that controls the rate of cholesterol production in the body, Simvastatin increases the liver's ability to collect and get rid of "bad cholesterol," raises "good cholesterol," and decreases triglycerides. You should not drink grapefruit juice while taking Simvastatin, as doing so can increase levels of Simvastatin in your blood, which can increase your risk of developing serious muscle problems.

 

What Is Simvastatin?

Simvastatin is a prescription medicine used for treating a number of conditions related to heart disease, including high cholesterol and high triglycerides. It is sold under the brand name Zocor®. It is also available as a generic, which is sold under the name Simvastatin tablets.
 

Simvastatin: Uses

Simvastatin has been licensed for several uses, including:
 
Simvastatin has also been approved for use in children ages 10 to 17 for the treatment of high cholesterol.
 

How Does Simvastatin Work?

Simvastatin is part of a class of drugs called statins.
 The medication works by blocking a particular enzyme (HMG-CoA reductase) that controls the rate of cholesterol production in the body. This causes the liver to make less cholesterol. Simvastatin also:
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;