Drug Interactions With Ruxolitinib

Some of the products that may cause drug interactions with ruxolitinib include certain immunosuppressants, live vaccines, and echinacea, among others. These negative reactions can affect the amount of the medications in your bloodstream or increase your risk for developing serious complications. To help minimize complications, tell your healthcare provider about all other medications, vitamins, or herbal supplements you are taking.

An Overview of Ruxolitinib Interactions

 Ruxolitinib (Jakafi™) may interact with a number of other medications. Some of the drugs that can lead to reactions with ruxolitinib include but are not limited to:
 
  • Certain immunosuppressants, such as:
 
 

 

 
  • CYP 3A4 inhibitor medications, such as:
 
 
 
 
 
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Written by/reviewed by: Susan Lakey, PharmD, MPH, BCPP
Last reviewed by: Kristi Monson, PharmD
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