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Rosuvastatin

Rosuvastatin is a drug licensed to treat high cholesterol and high triglycerides, among other conditions related to heart disease. It works by blocking an enzyme that controls the rate of cholesterol production in the body. In research studies, people taking it for high cholesterol were able to lower LDL cholesterol by up to 63 percent and total cholesterol by up to 40 percent.

Rosuvastatin Calcium

What Is Rosuvastatin?

Rosuvastatin calcium (Crestor^®) is a prescription medication used for treating a number of conditions related to heart disease, including high cholesterol and high triglycerides. Approved uses include:

Lowering cholesterol in people with high cholesterol (hypercholesterolemia). Rosuvastatin can reduce total cholesterol, LDL ("bad cholesterol"), ApoB, non-HDL cholesterol, and triglycerides -- as well as raise HDL ("good cholesterol").
Lowering triglycerides in people with high triglycerides (hypertriglyceridemia).
Treating dysbetalipoproteinemia, a rare genetic condition characterized by high cholesterol and triglyceride levels.
As an add-on treatment in people with homozygous familial hypercholesterolemia to help lower total and LDL cholesterol and increase HDL cholesterol.
Slowing the progression of atherosclerosis (a hardening and narrowing of the arteries).

(Click What Is Rosuvastatin Used For? for more information, including possible off-label uses.)

(Rosuvastatin Continued: Page 2)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD

Last reviewed by: Kristi Monson, PharmD;

Other Articles in This eMedTV Presentation

What Is Rosuvastatin Used For?

Rosuvastatin Side Effects

Dosing With Rosuvastatin

Drug Interactions With Rosuvastatin

Precautions and Warnings for Rosuvastatin

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