Drug Interactions With Risedronate

Risedronate Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when risedronate is combined with any of the drugs listed above.
 
Aspirin
Both aspirin and risedronate can be irritating to the stomach. Talk to your healthcare provider before taking aspirin if you are taking risedronate. Of course, no other medications (including aspirin) should be taken within 30 minutes of taking risedronate.
 
Calcium Products
Calcium binds to risedronate in the stomach, preventing it from being absorbed in the body and making it less effective. While it is usually important for people with osteoporosis to take calcium, it should not be taken within 30 minutes of taking risedronate.
 
Iron Supplements
Iron binds to risedronate in the stomach, preventing it from being absorbed in the body and making it less effective. Do not take iron supplements within 30 minutes of taking risedronate.
 
Magnesium Products
Magnesium binds to risedronate in the stomach, preventing it from being absorbed in the body and making it less effective. Do not take magnesium supplements within 30 minutes of taking risedronate.
 
Nonsteroidal Anti-Inflammatory Drugs
Both NSAIDs and risedronate can be irritating to the stomach. Talk to your healthcare provider before taking an NSAID if you are taking risedronate. Of course, no other medications (including NSAIDs) should be taken within 30 minutes of taking risedronate.
 
Teriparatide
In studies, combining teriparatide with medications like risedronate seemed to make teriparatide less effective. Talk to your healthcare provider before using these medications together.
 
(Drug Interactions With Risedronate Continued: Page 3)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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