Side Effects of Risedronate and Calcium (Cont.)

Serious Side Effects of Risedronate and Calcium

Some side effects of risedronate and calcium, while occurring infrequently, are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
 
  • Throat pain, chest pain, or difficulty swallowing (which may be signs of ulcers of the esophagus)
  • Severe heartburn or heartburn that does not go away
  • Severe bone, muscle, or joint pain
  • Jaw or tooth problems
  • Kidney stones
  • Signs of an allergic reaction, including unexplained rash, hives, itching, and unexplained swelling.
     

How to Minimize Side Effects of Risedronate and Calcium on the Esophagus

In order to reduce the chance of developing serious esophageal-related side effects, you should follow the prescribed directions on how to take risedronate and calcium. For example:
 
  • The risedronate tablets (the orange tablets) should be taken on an empty stomach and with a full glass of water first thing in the morning.
     
  • Swallow the risedronate tablets whole. Do not suck or chew on them.
     
  • For at least 30 minutes after taking the risedronate tablet, it is important to:
 
    • Remain in an upright position (either sitting up or standing). In fact, you should remain upright until you have had something to eat.
    • Wait to eat or drink. This includes mineral water, sparkling water, coffee, tea, milk, or juice. Plain water is okay.
    • Avoid taking any other oral medicine, including calcium supplements.
 

Final Thoughts on Side Effects of Risedronate and Calcium

You may experience some or none of the side effects of risedronate and calcium listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have side effects from a medicine that you have never tried. Therefore, make sure to let your healthcare provider know if you develop any side effects while taking the drug or if something "just does not seem right." While it may not be a side effect, your healthcare provider will be able to diagnose and treat the problem.
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;