Drug Interactions With Risedronate and Calcium

Risedronate and Calcium -- Drug Information

Drug Interactions With Risedronate and Calcium: An Overview

Risedronate and calcium (Actonel^® With Calcium) can potentially interact with a number of other medications. Many interactions can make the drug less effective, while others may increase the risk of side effects. Some of the medicines that may lead to drug interactions with risedronate and calcium include:

Aspirin

Calcium products, including many antacids

Fluoroquinolone antibiotics, such as:

Ciprofloxacin (Cipro^®)
Gatifloxacin (Tequin^®)
Levofloxacin (Levaquin^®)
Moxifloxacin (Avelox^®)
Norfloxacin (Noroxin^®)
Ofloxacin (Floxin^®)

Iron supplements

Magnesium products

Nonsteroidal anti-inflammatory drugs (NSAIDs), such as:

Celecoxib (Celebrex^®)
Diclofenac (Cataflam^®, Voltaren^®)
Etodolac (Lodine^®)
Ibuprofen (Motrin^®, Advil^®)
Indomethacin (Indocin^®)
Ketoprofen (Orudis^®)
Meloxicam (Mobic^®)
Nabumetone (Relafen^®)
Naproxen (Naprosyn^®) or naproxen sodium (Aleve^®, Anaprox^®, Naprelan^®)
Oxaprozin (Daypro^®)

Teriparatide (Forteo™)

Tetracycline antibiotics, such as:

Doxycycline (Periostat^®, Vibramycin^®)
Minocycline (Minocin^®)
Tetracycline (Sumycin^®)

Thyroid medications, such as:

Liothyronine (Cytomel^®)
Liotrix (Thyrolar^®)
Levothyroxine (Levoxyl^®, Synthroid^®, Unithroid^®)
Thyroid (Armour^® Thyroid, Nature-Throid^®).

Food and beverages (other than water) can also interact with risedronate (the orange tablets that are taken once a week), preventing it from being absorbed into the body and making it less effective. Risedronate should be taken with water in the morning on an empty stomach. Do not eat or drink anything (besides water) before taking the drug and for 30 minutes afterwards. On the other hand, the calcium tablets (the blue tablets that are taken the other six days of the week) should be taken with food.

(Drug Interactions With Risedronate and Calcium Continued: Page 2)