Drug Interactions With Rabeprazole

A number of different medications can cause rabeprazole drug interactions. Examples of products that can react with rabeprazole include digoxin, ketoconazole, and warfarin. If you are taking any of these medications, your doctor may choose to monitor your progress more closely.

An Introduction Rabeprazole Drug Interactions

Rabeprazole (Aciphex®) can potentially interact with a number of medications. Some of the medications that may lead to drug interactions with rabeprazole include:
 

More Details on Interactions With Rabeprazole

The following sections explain in detail the potentially negative interactions that can occur when rabeprazole is combined with any of the drugs listed above.
 
Atazanavir
Rabeprazole can substantially decrease the level of atazanavir in the blood (making it less effective). As a result, it is not recommended to take these two medications together.
 
Cyclosporine
Rabeprazole could potentially increase the level of cyclosporine in the blood. Check with your healthcare provider before combining cyclosporine with rabeprazole.
 
Digoxin
Rabeprazole could increase the absorption of digoxin into the blood, perhaps increasing the risk of digoxin side effects and toxicity. Check with your healthcare provider before combining these medications.

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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