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Drug Interactions With Rabeprazole

Rabeprazole could decrease the absorption of ketoconazole into the blood, perhaps making it less effective. Check with your healthcare provider before combining these medications.
Rabeprazole might increase the level of methotrexate in the blood, increasing the risk for methotrexate side effects. Check with your healthcare provider before combining these two medications.
There have been reports of increased international normalized ratio (INR) and prothrombin time results in people taking warfarin with rabeprazole. This indicates that combining these two medications may increase the risk of bleeding associated with warfarin. Your healthcare provider will probably need to monitor your INR more frequently and adjust accordingly.

Final Thoughts

It is possible that not all rabeprazole drug interactions were discussed in this article. Therefore, you should talk with your doctor about the specific interactions that may apply to you.

Rabeprazole Sodium

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