Questran

Questran is a prescription drug that is licensed for the treatment of high cholesterol and itching caused by partial biliary obstruction. It is a form of bile acid sequestrant that works by binding to bile acids in the intestines, preventing them from being reabsorbed. Questran comes in a powder form that should be mixed with liquids before consumed. Potential side effects include constipation, stomach discomfort, and gas.

 

What Is Questran?

Questran® (cholestyramine) is a prescription medication that is used to lower cholesterol levels in the body or control itching associated with certain types of liver disease.
 

Who Makes Questran?

Questran is manufactured by Bristol-Myers Squibb for Par Pharmaceuticals.
 

What Is Questran Used For?

Questran has been licensed for several uses, including:
 
  • Lowering LDL cholesterol (bad cholesterol) in patients with high total cholesterol
  • Relief of itching caused by a partial biliary obstruction.
     
(Click Questran Uses for more information on these specific uses.)
 

How Does Questran Work?

Questran is part of a class of drugs known as bile acid sequestrants. It works by binding to bile acids in the intestines, preventing them from being reabsorbed back into the body. Bile acids are made in the liver from broken-down cholesterol. Therefore, removing these substances from your body helps to lower your blood cholesterol. Questran can lower both total and LDL cholesterol.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;