Questran Drug Interactions

When certain medications, such as thiazide diuretics or oral phosphate supplements, are taken together with Questran, drug interactions may occur. It is recommended that you take most medicines at least one hour before or four to six hours after you take Questran to prevent a loss of effectiveness in the drugs. Other potential Questran drug interactions include estrogens and progestins, penicillin G, warfarin, and tetracycline.

 

Questran Drug Interactions: An Introduction

Questran® (cholestyramine) has the potential to interact with a number of other medications. Some of these Questran drug interactions include:
 
  • Warfarin (Coumadin®, Jantoven®)
  • Thiazide diuretics
  • Propranolol (Inderal®)
  • Tetracycline (Sumycin®, Achromycin®, Wesmycin®)
  • Penicillin G (Bicillin®, Pfizerpen®, Wycillin®)
  • Phenobarbital (Solfoton®)
  • Thyroid medicines
  • Estrogens and progestins
  • Digoxin (Digitek®, Lanoxin®, Lanoxicap®)
  • Oral phosphate supplements
  • Vitamin K products or phytonadione (Mephyton®)
  • Ursodiol (Actigall®)
  • Ezetimibe (Zetia®).
     
Warfarin
Questran may bind with warfarin in the intestines, preventing it from getting completely absorbed into the body. You can prevent this by taking warfarin at least one hour before or four to six hours after you take your Questran.
 
Thiazide Diuretics
Questran may bind with a thiazide diuretic in the intestines, preventing it from getting completely absorbed into the body. You can prevent this by taking a thiazide diuretic at least one hour before or four to six hours after you take your Questran.
(Questran Drug Interactions Continued: Page 2)
Add this article to your Favorites     Email this article     Print
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;