Drug Interactions With Pravastatin

Medications that may cause drug interactions with pravastatin include fibrates, erythromycin, niacin, and many others. These drug interactions may result in side effects or complications such as increased levels of medicine in the blood and an increased risk of developing serious muscle problems.

Drug Interactions With Pravastatin: An Introduction

There are a number of medications that can potentially interact with
 Pravastatin tablets("pravastatin"). Some possible pravastatin interactions can include:
 
  • Certain antifungals, such as:
 
    • Ketoconazole (Nizoral®), fluconazole (Diflucan®), and
    • Itraconazole (Sporanox®)
    • Ketoconazole (Nizoral®)
    • Miconazole
    • Posaconazole (Noxafil®)
    • Voriconazole (VFEND®)
 
  • Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
  • Erythromycin (Ery-Tab®)
  • Fibrates, such as:
 
 
  • Niacin (nicotinic acid, Niacor®, Nicolar®).
 
Some of these drug interactions may increase your risk for developing serious muscle problems (see Pravachol and Muscle Pain). If you experience unexplained muscle pain, tenderness, or weakness while taking pravastatin (especially if you also have a fever or feel ill), it is important to contact your healthcare provider immediately.
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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