Amiodarone (Cordarone)
Taking amiodarone and
pravastatin simultaneously may cause your body to metabolize the medicines differently than intended. This can cause significant reactions, including increasing the risk for developing serious muscle problems, such as myopathy or rhabdomyolysis. Your healthcare provider may choose to monitor your progress closely and make necessary dosing adjustments. Your pravastatin dosage should not exceed 40 mg per day.
Verapamil (Calan, Calan SR, Verelan, Verelan PM, Isoptin, Covera-HS)
Taking both
verapamil and pravastatin together may cause your body to metabolize the medicines differently than intended. This can cause significant reactions, including increasing the risk for developing serious muscle problems, such as myopathy or rhabdomyolysis. Your healthcare provider may choose to monitor your progress more closely and make necessary dosing adjustments. Your pravastatin dosage should not exceed 40 mg per day.
Digoxin (Digitek, Lanoxicaps, Lanoxin)
Taking digoxin with pravastatin appears to slightly increase the levels of digoxin in the blood. When starting pravastatin or increasing your pravastatin dosage, your healthcare provider may choose to monitor you more closely.
Cholestyramine (Prevalite, Questran, Questran Light, LoCholest)
Taking
cholestyramine and pravastatin together may cause a decrease of pravastatin in the blood, which can affect its ability to
lower cholesterol. It is recommended that you take cholestyramine either one hour before your pravastatin dose or four hours after your pravastatin dose.
Colestipol (Colestid)
Taking
colestipol and pravastatin together may cause a decrease of pravastatin in the blood, which can affect its ability to lower
cholesterol. It is recommended that you take colestipol either one hour before your pravastatin dose or four hours after.
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