More Detail About Pravastatin Interactions
Cyclosporine (Gengraf, Neoral, Sandimmune)
Taking both cyclosporine and
Pravastatin may cause your body to metabolize the medicines differently than intended. This can cause significant reactions, including increasing the risk for developing serious muscle problems, such as myopathy or rhabdomyolysis. Your healthcare provider may choose to monitor your progress more closely and make necessary dosing adjustments.
Danazol (Danocrine)
Taking danazol and pravastatin together may cause your body to metabolize the medicines differently than intended. This can cause significant reactions, including increasing the risk for developing serious muscle problems, such as myopathy or rhabdomyolysis. Your healthcare provider may choose to monitor your progress more closely and make necessary dosing adjustments.
Warfarin (Coumadin, Jantoven)
If you are taking pravastatin with warfarin, your body may metabolize the drugs differently than intended. When starting pravastatin therapy or changing the pravastatin dosage, your healthcare provider may choose to monitor your INR more closely and make any necessary adjustments. An INR is a test that measures how long it takes for your blood to clot.
Gemfibrozil (Lopid)
If you are taking pravastatin in conjunction with
gemfibrozil, your body may metabolize the drugs differently than intended. This can cause significant reactions, including increasing the risk for developing serious muscle problems, such as myopathy or rhabdomyolysis. Gemfibrozil and pravastatin are generally not recommended to be taken together.
Other Fibrates (Tricor, Antara, Lipofen, Triglide, Lofibra)
If you are taking both pravastatin and fibrates, your body may metabolize the medicines differently than intended. This can cause significant reactions, including increasing the risk for developing serious muscle problems, such as myopathy or rhabdomyolysis.
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