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Pomalidomide Side Effects

Common Side Effects

Pomalidomide has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking pomalidomide were carefully documented. As a result, it was possible to see what side effects occurred and how often they appeared.
Based on clinical studies, common pomalidomide side effects included but were not limited to:
  • Tiredness and weakness -- in up to 63 percent of people
  • Low white blood cell count, which could increase the risk for infection -- up to 52 percent
  • Shortness of breath -- up to 45 percent
  • Low red blood cell counts (anemia) -- up to 39 percent
  • Constipation -- up to 36 percent
  • Nausea -- up to 36 percent
  • Diarrhea -- up to 34 percent
  • Upper respiratory tract infection, such as the common cold -- up to 32 percent
  • Back pain -- up to 32 percent
  • Fever -- up to 30 percent
  • Pneumonia -- up to 29 percent.
Other common side effects, occurring in 10 percent to 25 percent of people, included but were not limited to:
  • Swelling due to fluid retention, especially of the arms, hands, legs, ankles, or feet
  • Low platelet counts, which could cause increased bruising or bleeding
  • Muscle, joint, or bone pain
  • Cough
  • Decreased appetite
  • Rash
  • Dizziness
  • High levels of calcium in the blood (hypercalcemia)
  • Muscle spasms
  • Urinary tract infection
  • Excessive sweating
  • Arm and leg pain
  • Increased blood sugar (hyperglycemia)
  • Nosebleeds
  • Night sweats
  • Changes in weight (weight gain or loss)
  • Insomnia
  • Low blood sodium levels (hyponatremia)
  • Low blood calcium levels (hypocalcemia)
  • Low blood potassium levels (hypokalemia)
  • Kidney failure
  • Tremor
  • Headache
  • Confusion
  • Muscle weakness
  • Chills
  • Anxiety
  • Dry skin
  • Itching
  • Numbness, tingling, or pricking sensations of the arms or feet.
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Pomalidomide Drug Information

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