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Pimozide Side Effects

Some of the most commonly reported side effects of pimozide are headaches, drowsiness, and a lack of energy. Fortunately, most reactions to this drug are minor and treated easily. There are, however, some potentially serious complications that require immediate medical treatment. Call your healthcare provider immediately if you experience problems such as unusual body movements, a forcefully beating heart, or a high fever.

An Introduction to Side Effects of Pimozide

Just like any medicine, pimozide (Orap®) can cause side effects. However, not everyone who takes the drug will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with pimozide. Your healthcare provider can discuss a more complete list with you.)
 

Serious Pimozide Side Effects

Some side effects of pimozide are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
 
  • Any unusual body movements, such as:
 
    • Feelings of internal restlessness or an inability to sit still
    • Tremors
    • Involuntary, uncontrollable facial, tongue, or body movements
    • Muscle stiffness, tension, or contractions
    • Spasms of the neck muscles
 
  • An abnormal, fast, or forcefully beating heart
  • High or low blood pressure (hypertension or hypotension)
  • Dizziness or fainting, especially upon rising from a seated or lying position
  • Weight gain
  • Signs of a serious condition known as neuroleptic malignant syndrome, such as:
 
    • High fever
    • Rigid muscles
    • Shaking
    • Confusion
    • Increased sweating
    • Increased heart rate
    • Increased blood pressure
    • Muscle pain or weakness
 
  • Seizures
  • Signs of an allergic reaction, such as:
 
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling
    • Wheezing
    • Difficulty breathing or swallowing.
 
Know the Signs - Concussion Safety

Pimozide Drug Information

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