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What Is Phenergan Used For?

Phenergan® (promethazine hydrochloride) is a sedating antihistamine approved for various uses. In general, Phenergan is used for:
  • Treating the following conditions:
    • Perennial (year-round) or seasonal allergies
    • Nonallergic nasal symptoms due to irritants
    • "Allergy eyes" (allergic conjunctivitis)
    • Hives
    • Allergic reactions to blood or plasma transfusions
    • Severe, anaphylactic allergic reactions (when used with other medications)
  • Treating or preventing nausea and vomiting related to surgery and general anesthesia (see Phenergan for Nausea)
  • Treating or preventing motion sickness
  • Causing sedation in the following situations:
    • Before or after surgery
    • During labor
    • In situations when mild anxiety relief and light sleep is desired.
Phenergan can also be combined with pain relievers for post-surgical pain. Occasionally, healthcare providers may also recommend this medication for "off-label" uses. For example, using the drug to treat morning sickness, coughing, and nausea or vomiting related to gastrointestinal illnesses are considered off-label uses for Phenergan.
(Click Phenergan Uses for more information on what this drug is used for, to find out if it is suitable for children, and for details on how Phenergan works for various conditions.)
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