Phenergan® (promethazine hydrochloride) is a prescription medicine used for a variety of purposes, including the treatment of nausea and vomiting. It comes in many different forms and can be taken by mouth (syrup and tablets) or inserted rectally (rectal suppositories). The drug can also be administered by injection at a hospital.
The brand-name tablets, syrup, and suppositories are no longer being manufactured (these products are only available in generic form now), but brand-name Phenergan injection is still available.
Great care should be taken if you are using the injection form of Phenergan, as improper administration can cause severe tissue damage, including gangrene. In some cases, amputations have resulted. This medication should not be given by "IV push" (when the drug is injected with a syringe rapidly into the IV line rather than dripped slowly into the line).
In most situations, it is best to give an injection of Phenergan directly into a muscle.
(Click Phenergan for more information on how to safely use Phenergan injection, to learn about other approved uses of this medicine, and to find out how it works.)