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Pentazocine/Naloxone Side Effects

It is possible to develop side effects while taking pentazocine/naloxone. Some of the possible reactions to this pain reliever include headaches, sweating, and constipation. While these types of problems are generally minor, serious complications can also occur. Seek medical treatment right away if you experience things like severe constipation, difficulty passing urine, or fainting.

An Introduction to Side Effects of Pentazocine/Naloxone

Just like any medicine, pentazocine/naloxone (Talwin® Nx) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with pentazocine/naloxone. Your healthcare provider can discuss a more complete list with you.)

Serious Pentazocine/Naloxone Side Effects

Some side effects of pentazocine/naloxone are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • The urge to take more pentazocine/naloxone than prescribed or take it for a non-medical purpose
  • High or low blood pressure (hypertension or hypotension)
  • Dizziness or fainting
  • A fast heartbeat
  • Slowed, shallow, or irregular breathing
  • Seeing or hearing things that are not real (hallucinations)
  • Feeling disoriented or confused
  • Seizures
  • Severe or persistent abdominal (stomach) pain
  • Severe or persistent constipation
  • Difficulty urinating
  • Numbness, burning, pricking, or other unusual sensations of the skin
  • Unusual behavior or mood, such as:
    • Depression
    • Irritability
    • Agitation
    • Unusual excitement
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.  
5 Common Pain Medication Fears

Pentazocine/Naloxone Information

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